Leprosy Bacteria Might Be Able To Regenerate Organs

The BBC reports: Leprosy bacteria may hold the secret to safely repairing and regenerating the body, researchers at the University of Edinburgh say. Animal experiments have uncovered the bacteria's remarkable ability to almost double the size of livers by stimulating healthy growth. It is a sneakily selfish act that gives the bacteria more tissue to infect. But working out how they do it could lead to new age-defying therapies, the scientists say.... The bacterium that causes [leprosy], Mycobacterium leprae, has other, unusual properties, including the ability to perform "biological alchemy", converting one type of bodily tissue into another, which are fascinating scientists. So the researchers turned to another animals that catches the disease — armadillos. The experiments, which were performed in the US, showed the infection heads to the armoured animals' livers, where it performed a controlled hijacking of the organ to reprogram it for its own purpose.... You might expect such growth to be defective or even cancerous — but detailed analysis showed it was both healthy and functional, complete with the usual array of blood vessels and bile ducts. "It is kind of mind-blowing," Prof Rambukkana said. "How do they do that? There is no cell therapy that can do that." The bacteria appears to be "rewinding the developmental clock" on the liver cells, the BBC writes, transforming them into a younger, faster-growing state. "The hope is the approach can be harnessed for repairing the livers of people waiting for a transplant — or even to reverse some of the damage caused by ageing elsewhere in the body." Thanks to long-time Slashdot reader Z00L00K for submitting the story!

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