NASA Astronauts Used CRISPR Gene Editing Technology For the First Time in Space

India's CNN-News18 reports: [P]revious research has found that how cells pick a particular repair strategy can be influenced by the microgravity conditions in space. Scientists are concerned that DNA repairs influenced by microgravity conditions may not be adequate, and can lead to harmful consequences. To study the DNA repair process in space, scientists have developed a new technique that uses CRISPR/Cas9 — a gene-editing technology — to recreate precise damages so that cells can be observed repairing them. The team of researchers led by Sarah Stahl-Rommel has successfully demonstrated the technique and its viability aboard the International Space Station. "CRISPR gene editing is no longer confined to Earth," reports Engadget: The new approach clears the way for other research around DNA repair in space. With enough work, the scientists hope they can replicate the genetic damage from ionizing radiation, not to mention other effects from long-term spaceflight. That, in turn, could help NASA and other agencies develop technology that shields astronauts and makes deep space exploration practical. There's a chance CRISPR might play an important role in getting humans to Mars and beyond.

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