Scientists Discover 'Why Stress Turns Hair White'

An anonymous reader quotes a report from the BBC: Scientists say they may have discovered why stress makes hair turn white, and a potential way of stopping it happening without reaching for the dye. Researchers behind the study, published in Nature, from the Universities of Sao Paulo and Harvard, believed the effects were linked to melanocyte stem cells, which produce melanin and are responsible for hair and skin color. And while carrying out in experiments on mice, they stumbled across evidence this was the case. Pain in mice triggered the release of adrenaline and cortisol, making their hearts beat faster and blood pressure rise, affecting the nervous system and causing acute stress. This process then sped up the depletion of stem cells that produced melanin in hair follicles. In another experiment, the researchers found they could block the changes by giving the mice an anti-hypertensive, which treats high blood pressure. And by comparing the genes of mice in pain with other mice, they could identify the protein involved in causing damage to stem cells from stress. When this protein -- cyclin-dependent kinase (CDK) -- was suppressed, the treatment also prevented a change in the color of their fur. This leaves the door open for scientists to help delay the onset of grey hair by targeting CDK with a drug.

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