Mammals Can Breathe Through Their Intestines

fahrbot-bot shares a report from Gizmodo: When pressed for oxygen, some fish and sea cucumbers will use their lower intestines to get a little extra out of their environment. Now, a team of Japanese researchers say that mammals are also capable of respirating through their rectal cavity, at least in a lab setting. The team's research is published today in the journal Med and describes the capacity for mice, rats, and pigs to survive longer and have more strength in low-oxygen circumstances when given oxygen gas or an oxygen-rich liquid through their rectums, in a process similar to an enema. While fish like loaches and catfish use a similar method to gain additional oxygen in the natural world, this doesn't appear to be an evolutionary adaptation for mammals. In other words, mammalian bodies can't naturally do this, but with a little push from modern science, it becomes possible. Previous research has seen oxygen injected directly into mammalian bloodstreams, prolonging the lives of rabbits, but the rectal approach to the low-oxygen problem is novel. The experiment, while disturbing, was designed to find new ways to save the lives of people whose lungs are failing. These treatments prolonged the animals' survival in a low-oxygen setting by staving off respiratory failure. Mice were given both the gas and liquid oxygen delivery methods, while the rats and pigs only received the liquid treatment. In a lab-controlled hypoxic setting (a chamber that was 9.5% oxygenated), mice without the supplemental oxygenation died after about 11 minutes. With the treatment, three-quarters of the tested mice survived for nearly an hour in the same lethal conditions. ScienceAlert adds these details: Initially, their research subjects were mice, who were thankfully anesthetized for the next part. The researchers developed an oxygen ventilation system to be inserted anally; they induced hypoxia via tracheal intubation, and compared mice ventilated intestinally to control mice who received no ventilation. Of the control mice, not a single one survived longer than 11 minutes. This was in marked contrast to the mice receiving intestinal oxygen, 75 percent of which survived for 50 minutes.

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